A team of researchers, led by an Indian-origin scientist has identified two new cancer-causing gene mutations. This discovery is expected to lead more targeted and effective treatments for certain type of lung and prostate cancers.
The researchers believe that cancers with the newly discovered mutations in the MCM8 and MCM9 genes will respond to certain specific drugs already approved by US Food and Drug Administration (USFDA) to treat breast cancers with BRCA1 and BRCA2 gene mutations. As of now, there is no commercially available diagnostic test for the mentioned MCM8 and MCM9 type mutations
Dr. Anindya Dutta, the lead researcher and the professor at University of Virginia School of Medicine in the US, said “One of the biggest problems in cancer is that we hit everything with the same hammer, and consequently some cancers are responsive and others are not. Imagine if you could find the perfect hammer for the nail - the famous personalised therapy".
The findings have been detailed online in the journal - Nature Communications.